Severe Reactions to DTP Vaccine

DTP vaccine related injury: an examination of proposed vaccine injury compensation legislation.

Earlier infantile immune maturation is related to higher DTP vaccine responses in children

There are large inter-individual variations in vaccine-specific antibody responses in children. We sought to investigate whether early-life environmental factors and/or adaptive immune maturation were related to diphtheria-tetanus-pertussis (DTP) vaccine-specific antibody levels at 18 months of age. In the prospective FARMFLORA birth-cohort, including both farming and non-farming families, chil...

VII. Reactions to the Oral Vaccine ‡

As described in earlier papers in this series, approximately 10,000 persons, mainly children between the ages of 3 months and 18 years, were given the Sabin oral poliovirus vaccine in Middletown, Connecticut, early in 1961. Among the objectives of the program was the detection of any contra-indications or untoward effects which might follow the use of the oral vaccine. The following discussion ...

Severe cutaneous adverse reactions to drugs.

PURPOSE OF REVIEW This paper updates the treatment of Stevens-Johnson syndrome and toxic epidermal necrolysis supported by relevant views about the pathogenesis. RECENT FINDINGS Building on the thesis that Stevens-Johnson syndrome and toxic epidermal necrolysis are due to dermal cell apoptosis, molecular pathways that may lead to this have been proposed. Intravenous immunoglobulin is postulat...

Severe allergic reactions to guinea pig

BACKGROUND Allergic sensitization and reactions to guinea pig (Cavia porcellus) have been well documented in laboratory animal handlers, primarily manifesting as rhinitis, conjunctivitis, and asthma. Severe allergic reactions, however, are rare. METHODS We report two patients with severe allergic reactions following non-occupational exposure to guinea pigs. The first patient, an 11-year-old f...